Why shelton had parkinsons




















I have completed about fifty paintings during that time. I give them as gifts to family and friends and the activity helps me to forget my symptoms. I also love caring for my house, reading, gardening and piece jig saw puzzles.

Mirapex and Carbidopa-levo are the two drugs that work for me. All others have been disappointing due to side effects, especially the Neupro patch which caused heavy suicidal thoughts. Parcopa quickly caused my hair to fall out. I promptly stopped taking it and my hair is finally growing back. At this stage, I have a lot of dyskenesias and rigidity in my back, but I keep moving and doing as much as I can.

I have some trouble swallowing and loss of appetite which has led to weight loss. I have learned some swallowing techniques from a speech therapist, softened my diet and increased my calorie intake. So far, so good. Otherwise, life is good with a loving husband and family giving me generous support. I live in the moment…one day at a time.

Attitude to me is more important than facts. It is more important than the past, than education, than money, than circumstances, than failures, than successes, than what other people think or say or do. It is more important than appearance, giftedness, or skill. It will make or break a company…a church…a home.

The remarkable thing is we have a choice every day regarding the attitude we will embrace for that day. We cannot change our past…we cannot change the fact that people will act in a certain way. We cannot change the inevitable. The only thing we can do is play on the one string we have, and that is our attitude. And so it is with you…we are in charge of our attitude! We are proud to have you as a part of our community.

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The Parkinson's Foundation is a c 3 nonprofit organization. EIN: Find Resources Near You. Search Our Site. Menu Close. Understanding Parkinson's What Is Parkinson's? Physical therapy may also be recommended to improve mobility, range of motion and muscle tone.

Daily activities may become difficult for patients with Parkinson's disease and an occupational therapist may be helpful in guiding them through techniques to make daily tasks easier.

It is important for patients with Parkinson's disease to have a strong support system so that they can physically and emotionally cope with the disease. Some patients may benefit from Parkinson's disease support groups. Parkinson's Disease Parkinson's disease is a progressive motor system disorder that occurs when certain cells within the brain begin to degenerate or break down. Causes of Parkinson's Disease Parkinson's disease is caused by the breakdown of dopamine-producing cells within the brain.

Symptoms of Parkinson's Disease Many patients with Parkinson's disease may notice a slight tremor as their initial symptom, which usually begins in one arm or leg and slowly spreads to other areas of the body. Additional symptoms associated with Parkinson's disease may develop over time and include the following: Tremors or shaking Stiffness in the muscles Slow movement Difficulty walking or balancing Impaired posture and balance Slurred speech As the symptoms of Parkinson's disease become more pronounced, patients may have difficulty walking, talking, or completing other simple tasks Complications of Parkinson's Disease Parkinson's disease is a degenerative and chronic condition, that may eventually lead to serious complications if left untreated.

Over time, many patients with this condition may also experience: Depression Sleep problems Difficulty swallowing Constipation Sexual dysfunction Blood pressure may also be affected by Parkinson's disease and patients may experience pain in specific areas or throughout the body. Diagnosis of Parkinson's Disease If Parkinson's disease is suspected, symptoms are reviewed and a physical examination is performed. Treatment of Parkinson's Disease Although there is no cure available for Parkinson's disease, there are many treatments available to help control symptoms.

Other medications commonly prescribed for Parkinson's disease may include: Dopamine agonists MAO-B inhibitors Anticholinergics Amantadine Patients with advanced stages of Parkinson's disease who are not be responding to medication, may benefit from a surgical procedure known as deep brain stimulation.

Coping with Parkinson's Disease It is important for patients with Parkinson's disease to receive regular exercise to increase muscle strength and flexibility and maintain function throughout the body. Kummer, A. Psychiatry Rev. Todes, C. Psychiatry 48 , 97— Heberlein, I. Psychiatry 64 , — Sieurin, J.

Personality traits and the risk for Parkinson disease: a prospective study. Poletti, M. Chen, H. Cassani, E. Hellenbrand, W. I: a possible role for the past intake of specific foods and food groups. Results from a self-administered food-frequency questionnaire in a case-control study. Neurology 47 , — Qin, X. Aberrations in peripheral inflammatory cytokine levels in Parkinson disease. Bower, J. Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: a case-control study.

Neurology 67 , — Cheng, C. Allergy 70 , — Savica, R. When does Parkinson disease start? Rajkomar, A. Scalable and accurate Deep learning for electronic health records. Nalls, M. Lancet Neurol. Burke, R. Dorsey, E. Health 0 , 1—18 Chang, D. Hughes, A. Psychiatry 55 , — Do, C. PLoS Genet. Van Den Eeden, S. Wright Willis, A. Geographic and ethnic variation in Parkinson disease: a population-based study of us medicare beneficiaries.

Neuroepidemiology 34 , — Durand, E. Ancestry composition: a novel, efficient pipeline for ancestry deconvolution. Henn, B. Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples. Postuma, R. Download references. We thank the customers of 23andMe who answered surveys and participated in this research.

Study funding: Supported by The Michael J. Agee 1 , A. Auton 1 , R. Bell 1 , K. Bryc 1 , S. Elson 1 , N. Furlotte 1 , D. Hinds 1 , J. McCreight 1 , K. Huber 1 , A. Kleinman 1 , N. Litterman 1 , M. McIntyre 1 , J. Mountain 1 , E. Noblin 1 , C. Northover 1 , S. Pitts 1 , J. Sathirapongsasuti 1 , O. Sazonova 1 , J. Shelton 1 , S. Shringarpure 1 , C. Tian 1 , J. Tung 1 , V. Vacic 1 , C. Wilson 1.

Agee, A. Auton, R. Bell, K. Bryc, S. Elson, N. Furlotte, D. Hinds, J. McCreight, K. Huber, A. Kleinman, N. Litterman, M. McIntyre, J. Mountain, E. Noblin, C. Northover, S. Pitts, J. Sathirapongsasuti, O. Sazonova, J. Shelton, S. Shringarpure, C. Tian, J. Tung, V. Vacic, C. You can also search for this author in PubMed Google Scholar. Study concept and design: K. Acquisition, analysis, or interpretation of data: all authors. Drafting of the manuscript: K. Critical revision of the manuscript for important intellectual content: all authors.

Statistical analysis: K. Obtained funding: P. Administrative, technical, or material support: The 23andMe Research Team. Correspondence to Karl Heilbron. Heilbron, Fontanillas, Alipanahi, Cannon, and members of the 23andMe Research Team are employees of and have stock, stock options, or both, in 23andMe. The remaining authors declare no competing interests. Reprints and Permissions. Heilbron, K. Download citation.



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